Systemic inflammation affects reperfusion following transient cerebral ischaemia
نویسندگان
چکیده
منابع مشابه
Systemic inflammation affects reperfusion following transient cerebral ischaemia
Reperfusion after stroke is critical for improved patient survival and recovery and can be achieved clinically through pharmacological (recombinant tissue plasminogen activator) or physical (endovascular intervention) means. Yet these approaches remain confined to a small percentage of stroke patients, often with incomplete reperfusion, and therefore there is an urgent need to learn more about ...
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A 51-year-old vintner entered hospital because of episodes of transient cerebral ischaemia. These had begun six months previously and occurred about twice weekly. They were provoked by the physical exertion of lifting crates and barrels so regularly that he had to leave his employment. At other times he experienced attacks while sitting. There was no relation to movements of the neck. Each atta...
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Using the hydrogen clearance technique, local cerebral blood flow (LCBF) in 22 dogs was estimated at 6 parietal sites prior to and following 5 min of total global ischemia. Ischemia was immediately followed by an initial reactive hyperemia during which the electrocorticogram (ECoG) usually began to recover, and within the first 30 min, most of the LCBF's decreased to subnormal values. This onse...
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Following 5 minutes of global ischemia, local cerebral blood flow (LCBF) was shown to have an initial reactive hyperemia that was followed, within the first hour, by persistent hypoperfusion (Part I). Intracranial pressure (ICP) was never elevated during the period of poor reperfusion. These experiments attempted to reverse the state of subnormal LCBF by inducing hypercarbia or hyocarbia or mai...
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ژورنال
عنوان ژورنال: Experimental Neurology
سال: 2016
ISSN: 0014-4886
DOI: 10.1016/j.expneurol.2016.01.013